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modafinil will lessen the level or effect of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.saquinavir will enhance the level or effect of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.Keep track of Closely (1)mitotane decreases amounts of modafinil by affecting hepatic